Recent and related publications

School Contact Information

Koret School of Veterinary Medicine,
The Robert H. Smith Faculty of Agricultural, Food & Environment,
The Hebrew University of Jerusalem.

Address: Herzl 229, P.O. Box 12,
Rehovot 76100, Israel

Phone: +972-(0)8-9489021/31;
Fax: +972-(0)8-9467940
E-Mail: vet.school@mail.huji.ac.il

 

  1. Barkan D, Liu Z, Sacchettinni JC, Glickman MS. (2009) Mycolic Acid Cyclopropanation is Essential for Viability, Drug Resistance, and Cell Wall Integrity of Mycobacterium tuberculosisChemistry & Biology 16, 499–509
  2. Barkan D, Rao V, Sukenick GD, Glickman MS. (2010). Redundant function of cmaA2 and mmaA2 in Mycobacterium tuberculosis cis-cyclopropanation of oxygenated mycolates. Journal of Bacteriology. July; 3661–3668.
  3. Barkan D, Stallings CS, Glickman MS: (2010) An improved counterselectable marker system for mycobacterial recombination using galK and 2-Deoxy-Galactose. Gene; (470) 31-6.
  4. Gupta R, Barkan D, Redelman-Sidi G, Shuman S, Glickman MS: (2011) Mycobacteria exploit three genetically distinct DNA double-strand brake repair Pathways. Molecular Microbiology, Jan; 79(2) :316-30.
  5. Barkan D, Hedhli D, Han-Guang Y, Huygen K, Glickman MS: (2012) M. tuberculosis lacking all mycolic acid cyclopropanation is viable but highly attenuated and hyperinflammatory in mice. Infection and Immunity, Jun;80(6):1958-68
  6. Vanunu MS, Lang ZS, Barkan DPI: (2017). The gene fmt, encoding tRNAfMet-formyl transferase, is essential for normal growth of M. bovis, but not for viability. Sci Rep. 2017 Nov 9;7(1):15161 
  7.  Hu Z, Zhao HM, Li CL, Liu XH, Barkan DC, Lawrie DB, Lu SH, Fan XY. (2018) The role of KLRG1 in human CD4+ T cell immunity against tuberculosis. J Infect Dis.  Jan 24.
  8. Meir MC, Grosfeld TS, Barkan DPI: (2018). Establishment and validation of Galleria mellonella as a novel model organism to study Mycobacterium abscessus infection, pathogenesis and treatment. Antimicrobial Agents and Chemotherapy. 2018 Mar 27;62(4) 
  9. Velasquez LN, Stüve P, Gentilini MV, Swallow M, Bartel J, Lycke NY, Barkan DC, Martina M, Lujan HD, Kalay H, van Kooyk Y, Sparwasser TD, Berod L (2018) Targeting Mycobacterium tuberculosis Antigens to Dendritic Cells via the DC-SIGN Receptor Induces Strong Th1 Immune Responses. Frontiers in Immunology, 2018 Mar 9;9:471. doi: 10.3389/fimmu.2018.00471 
  10. Rakovitsky NPD, Bar Oz MS, Goldberg KS, Gibbons SC, Zimhony OC, Barkan DPI (2018)  The unexpected essentiality of glnA2 in Mycobacterium smegmatis is salvaged by the global nitrogen regulator glnR, but not by L-, D-, or iso-glutamine. Frontiers in Microbiology, 11 September, 2018. doi: 10.3389/fmicb.2018.02143 
  11. Meir MC, Bifani PC, Barkan DPI (2018). Addition of avibactam renders M. abscessus sensitive to piperacillin in an in-vivo infection model. Antimicrobial Resistance & Infec. Control, Dec 13;7, 151. doi: 10.1186/s13756-018-0448-4 
  12. Vanunu MS, Schall PS, Reingewertz THPD, Chakraborti PKC, Grimm BC, Barkan DPI (2019). MapB protein is the essential methionine aminopeptidase in Mycobacterium tuberculosis. Cells, 2019, Apr 28;8(5). pii: E393. doi: 10.3390/cells8050393. 
  13. Naor NS, Gadot OS, Meir MC, Barkan DPI (2019). Peptide Deformylase (def) is essential in Mycobacterium smegmatis, but the essentiality is compensated by inactivation of methionine formylation. BMC Microbiology, Oct 26;19(1):232. doi: 10.1186/s12866-019-1611-7. 
  14. Reingewertz THPD, Meyer TS, McIntosh F, Sullivan J, Meir MC, Chang YFC, Behr MAC, Barkan DPI (2020): Differential sensitivity of mycobacteria to isoniazid is related to differences in KatG-mediated enzymatic activation of the drug. Jan 27;64(2). Antimicrobial Agents and Chemotherapy
  15. Meir Mc, Rozenblit As, Fliger Ss, Geffen Yc, Barkan DPI (2020) EttA is likely non-essential in Staphylococcus aureus persistence, fitness or resistance to antibiotics. BMC Microbiology. Sep 17;20(1):288. doi: 10.1186/s12866-020-01970-w     
  16. Foreman Ms, Gershoni Mc, Barkan DPI (2020). A simplified and efficient method for Himar-1 Transposon-sequencing in bacteria, demonstrated by creation and analysis of a saturated transposon-mutant library in Mycobacterium abscessus. mSystems, Oct. 20. DOI: 10.1128/mSystems.00976-20
  17. Watson A, Li H, Ma B, Weiss R, Bendayan D, Abramovitz L, Ben-Shalom N, Mor M, Pinko E, Bar Oz MS, Wang Z, Du F, Lu Y, Rybniker J, Dahan R, Huang H, Barkan DC, Xiang Y, Javid B, Freund NTPI. (2021) Human antibodies targeting a Mycobacterium transporter protein mediate protection against tuberculosis. Nature communications, Jan 27;12(1):602. doi: 10.1038/s41467-021-20930-0

 

See also: daniel_barkan